معرفی
Xiaowen Bai, MD, PhD, is a Professor in the Department of Cell Biology, Neurobiology and Anatomy at the Medical College of Wisconsin. His research focuses on leveraging stem cells to model neurodegenerative diseases and cardiac disorders, with a particular emphasis on non-coding RNAs, mitochondria, and environmental stressors like anesthetics and alcohol. He holds a leadership role as Executive Director of Hematology at the World Federation of Chinese Medicine Societies (WFCMS).
Education:
- MD, Shanxi Medical University (1993)
- PhD, Beijing University Stem Cell Center (2004)
- Postdoctoral Training, University of Texas MD Anderson Cancer Center (2007)
Research Interests:
- Neurodegeneration mechanisms involving microRNAs, lncRNAs, and mitochondrial dysfunction
- Stem cell-based therapies for myocardial regeneration
- Diabetic cardiomyopathy pathogenesis and cardioprotection
- 3D organoid models for studying anesthetic and alcohol neurotoxicity
Recent Work: Recent publications emphasize translational studies using human-induced pluripotent stem cell (iPSC)-derived models to investigate alcohol-induced brain injury, anesthetic neurotoxicity, and cardiac fibrosis. His lab also explores immunomodulatory pathways and redox signaling in inflammatory diseases.
Labs/Teams: The Bai Lab develops novel in vitro models for disease modeling and drug testing, focusing on cerebral organoids and cardiac organoids to bridge basic research and clinical applications.
