William Winston Agace

William Winston Agace is a Professor at the Department of Health Technology, Technical University of Denmark, specializing in Experimental & Translational Immunology within the DTU Microbes Initiative.

• Contact: wiag@dtu.dk | ORCID | Website

His research focuses on intestinal immune compartments, particularly dendritic cells, T cell homeostasis, and stromal cell biology, with implications for colitis, autoimmune diseases, and gut-microbiome interactions. Recent work explores cDC1-IL-27 signaling, neutrophil immunopathology, and embryonic Gli1+ precursor lineages in intestinal development.

• Key Trends (2022-2023):
  • Mouse models for mucosal immunity
  • Single-cell RNA sequencing in immune cell heterogeneity
  • Adjuvant mechanisms in influenza protection
  • Stromal cell dynamics in gut homeostasis

Supervision: Main supervisor for PhD candidates Junghus, F. (Crohn's disease immune compartments), Christensen, L. W. (intestinal mononuclear phagocytes), and Pærregaard, S. I. (intestinal stromal cell lineage tracing).