William Schwan

William Schwan is a Professor in the Department of Microbiology at the University of Wisconsin-La Crosse. His research focuses on bacterial pathogenesis, host responses to infections, and drug discovery targeting Gram-positive pathogens.

• B.S., Quincy College
• M.S., Iowa State University
• Ph.D., Northwestern University
• Postdoctoral Research, University of Würzburg and FDA

His research spans Staphylococcus aureus and uropathogenic Escherichia coli (UPEC), investigating gene regulation related to virulence factors like biofilms and fimbriae. He employs genetic, molecular, and animal models to explore these mechanisms.

Recent publications highlight his work on:

• SK-03-92's effects on S. aureus and M. tuberculosis
• Proline transport mutants in S. aureus
• Two-component regulatory systems in biofilm formation
• Fim gene regulation in UPEC under acidic/murine infection conditions
• Molecular approaches to drug discovery

William Schwan's lab actively involves 3-6 undergraduate students per semester, with several co-authoring peer-reviewed articles. His teaching includes courses in Pathogenic Bacteriology, Global Impact of Infectious Disease, and Microbial Pathogenicity.

Key affiliations and collaborations include:

• University of Wisconsin-La Crosse (since 2000s)
• University of Wisconsin-Madison (presentations)
• University of Würzburg (postdoctoral research)
• Centers for disease research involving murine models and molecular techniques