William M. Jacobs

William M. Jacobs is an Assistant Professor of Chemistry at Princeton University, affiliated with the Frick Chemistry Laboratory. His research focuses on the theoretical and computational study of biomolecular self-assembly and soft materials, particularly exploring how heterogeneity and nonequilibrium processes influence phase separation and self-assembly in biological systems. His work combines statistical mechanics, coarse-grained modeling, and multiscale simulations to predict and design complex nanoscale structures.

**Research Interests:** Jacobs' group investigates multicomponent phase behavior, nonequilibrium phase transformations, and protocol design for optimizing self-assembly reactions. Key areas include biomolecular condensates, DNA-coated colloids, and programmable materials. Their research bridges chemistry, biophysics, and materials science to address challenges in bio-mimetic material design and cellular organization.

**Honors & Awards:** Jacobs has received prestigious recognitions, including the NIH R35 MIRA Early Stage Investigator Award (2024), NSF CAREER Award (2021), and Princeton Engineering Commendation for Outstanding Teaching (2023). His work is supported by grants such as the NIH and NSF funding.

**Grants & Advising:** His research is funded by NIH and NSF grants, and he collaborates widely with experimental groups. While specific student advisees are not listed, his group actively publishes with postdocs and students on topics like phase-separated condensates and nonequilibrium dynamics.

**Lab & Team:** The Jacobs Group is based at Frick Chemistry Laboratory, Princeton, and maintains an active website detailing their research on biomolecular self-assembly and soft materials.