William A. Coetzee
استاد · Ion translocation mechanisms (channels, exchangers, pumps)
New York Universityمعرفی
Professor William A. Coetzee holds appointments in four departments at NYU Grossman School of Medicine: Pathology, Biochemistry and Molecular Pharmacology, Neuroscience, and Pediatrics. His research focuses on ion translocation mechanisms, particularly the ATP-sensitive potassium (KATP) channel, which bridges intracellular metabolism with membrane excitability.
The Coetzee Laboratory investigates KATP channels in cardioprotection, blood flow regulation, and immune cell function, using patch clamping, biochemistry, and genetically engineered mouse models. Collaborative work with the New York City Office of the Chief Medical Examiner explores genetic variations in ion channel genes linked to sudden unexplained death.
Recent publications highlight his work on KATP channel roles in immunity, Rab35-mediated endocytic recycling, sirtuin-cardioprotection interactions, and novel channel activators. Collaborative studies emphasize channel trafficking dynamics in cardiac and immune systems.
Contact: William.Coetzee@nyulangone.org | Lab: Coetzee Laboratory
