معرفی
Dr. Wei Ba is a Researcher in the Department of Life Sciences at Imperial College London, affiliated with the Faculty of Natural Sciences. Based at the Sir Ernst Chain Building on the South Kensington Campus, their work focuses on neurophysiological mechanisms, synaptic function, and neurodevelopmental disorders. Dr. Ba's research explores the interplay between neural circuits and behaviors, particularly in contexts such as sleep regulation, anxiety, and intellectual disability.
Research interests include the role of GABAergic and glutamatergic systems in sleep-wake cycles, basal ganglia circuits in anxiety regulation, and the genetic and molecular basis of neurodevelopmental disorders. Their studies often employ animal models to investigate synaptic plasticity, epigenetic regulation (e.g., histone methylation), and the impact of genetic mutations on neuronal function.
Notable contributions include identifying neuronal hubs linking sleep initiation with thermoregulation, elucidating how GABA B receptor signaling contributes to schizophrenia-like phenotypes in rats, and discovering mechanisms underlying intellectual disability via proteins like SVBP and TRIO. Dr. Ba's work bridges molecular neuroscience with behavioral outcomes, addressing fundamental questions in neural circuitry and disease pathophysiology.
