معرفی
Dr. Upasna Srivastava is an Associate Research Scientist in Neurology at Yale School of Medicine's Rangaraju Lab. She holds a Ph.D. and completed postdoctoral training at the University of Tokyo (under Prof. Koji Tsuda) and the University of California San Diego (collaborating with Dr. Kelan Tantisira). Her expertise spans proteomics, single-cell RNA sequencing (snRNAseq), microbiome analysis, and cancer research, with a focus on neurological disorders like stroke and Alzheimer's disease. She has collaborated with leading researchers including Dr. Ryoji Yao and Prof. Vaccarino Flora.
Research Interests: Dr. Srivastava's work integrates multi-omics approaches to study neuroinflammatory mechanisms, astrocyte biology, and drug response in asthma. Her studies leverage proteomics to uncover disease pathways in Alzheimer's and stroke, alongside miRNA biomarkers for asthma subtyping. She also explores computational models to understand cancer protein interactions and drug targets.
Key Contributions: Recent work includes identifying Kv1.3 channel-interacting proteins in T-cells, astrocyte-specific proteomic changes post-stroke, and miRNA associations with asthma exacerbations. Her methods bridge clinical and basic science, with applications in drug development and precision medicine.
Professional Activities: Editorial roles include Frontiers in Neuroinformatics and BMC Genomics. She is a member of the American Thoracic Society and ISTAART. Her talks include sessions on single-cell analysis in crop improvement and asthma pharmacogenetics.
