معرفی
Ulrika Yngve is a medicinal chemist at Uppsala University, working in the Department of Medicinal Chemistry and leading the Facility for Medicinal Chemistry within the Drug Discovery and Development Platform at Science for Life Laboratory. With 12 years of industrial experience at AstraZeneca, she specializes in collaborative drug discovery projects that deliver high-quality compounds for academic research.
Research Interests
- Design and optimization of enzyme inhibitors for therapeutic applications
- Development of radiolabeled compounds for PET imaging
- Modulation of gamma-secretase and beta-secretase pathways in Alzheimer's disease
- Targeting ion channels for pain management therapies
- Improving metabolic stability of drug candidates
- Application of automated GMP-compliant synthesis methods
Notable Article Trends: Recent publications focus on enzyme inhibition strategies (DHODH, GSK3, gamma-secretase), neuroimaging probes for amyloid-related pathologies, and sodium channel blockers for pain models. These works emphasize translational research bridging medicinal chemistry with clinical applications.
Laboratory Affiliation: Leads the Facility for Medicinal Chemistry at SciLifeLab, contributing to interdisciplinary collaborations between academia and pharmaceutical research.
