TuKiet Lam

TuKiet Lam is a Research Scientist and Director of the Keck MS & Proteomics Resource at Yale School of Medicine's Department of Molecular Biophysics and Biochemistry. He specializes in mass spectrometry (MS) and proteomics, providing advanced instrumentation and analyses for interdisciplinary research in biological, clinical, and pharmaceutical fields. His career includes leadership roles at the National High Magnetic Field Laboratory and Florida State University.

Education:

• BS in Chemistry, Rollins College (1998)
• PhD in Analytical Chemistry, Florida State University (2002)
• Postdoctoral Training at National High Magnetic Field Laboratory (2003)

Research Focus: Dr. Lam’s work focuses on applying high-resolution mass spectrometry to study protein interactions, posttranslational modifications, and biomarkers in diseases like Alzheimer’s, cancer, and cardiovascular disorders. His lab collaborates widely, contributing to over 125 publications.

Key Projects:

• Proteomic profiling of Alzheimer’s axonal pathology
• Cerebrospinal fluid biomarker discovery for neurodegenerative diseases
• Metabolite analysis in preterm birth and diabetes
• Drug metabolism and cannabinoid effects on brain proteomes

Labs & Resources: Director of the Keck MS & Proteomics Resource, a core facility supporting Yale researchers with state-of-the-art MS technologies. The lab emphasizes reproducible methodologies for protein quantitation, PTM analysis, and small molecule characterization.