Tracy Warr

Professor Tracy Warr is a leading neuro-oncology researcher at the University of Wolverhampton's Research Institute in Healthcare Science, with over 25 years of experience in experimental brain tumour research. Previously at University College London's Institute of Neurology, she established a research programme focused on glioma treatment outcomes since 2009. Her work spans genomic/epigenetic analysis, metabolic therapies, and tumour immunosuppression.

• PhD, University of Wales Swansea (1991)
• BSc, University of Leeds (1986)

Research Themes:

• Therapeutic target validation in paediatric/adult gliomas
• Metabolic dysregulation and repositioned drugs
• Epigenetic mechanisms in brain metastases
• Tumour-mediated immunosuppression in GBM
• Pre-clinical model development
• Dietary modulation of cancer progression

Publication Trends: Recent work focuses on non-coding RNA methylation patterns in metastatic breast cancer, hexokinase 2's epigenetic regulation in glioblastoma, and arginine biosynthesis pathway inactivation in paediatric high-grade gliomas. Earlier studies explored PDE1C's role in tumour proliferation, flavonoid effects on invasion, and p53 dynamics in chromosomal instability.

Scientific Recognition:

• Honorary Professor, Third Military Medical University (2012)

Advising & Grants: Supervised numerous PhD projects on topics like metformin therapy, miRNA roles in angiogenesis, and secretomic analysis of GBM immunosuppression. Current research funded by grants including "Unravelling T cell immunosuppression" (Headcase Cancer Trust) and "Role of miR-133a" (Royal Wolverhampton NHS Trust).