Ton Boersma

Ton Boersma is a Researcher at Erasmus University Medical Center in Rotterdam, Netherlands, with a significant research output focused on cancer biology and pharmacology. His work primarily investigates the role of microRNAs in cancer drug resistance and sensitivity mechanisms.

His research interests center on molecular oncology, particularly in the areas of microRNA biology and drug resistance mechanisms in cancer treatment. Boersma's work demonstrates strong connections to cisplatin pharmacology (100%), ovarian cancer research (90%), and cancer cell line studies (72%). His research examines how microRNAs regulate cellular responses to cancer therapies, with applications in personalized medicine approaches.

Analysis of his publication record reveals a consistent focus on microRNA-mediated regulation of cancer cell responses to treatment. His most cited work explores how specific microRNAs like miR-634 can restore drug sensitivity in resistant ovarian cancer cells by targeting key signaling pathways like Ras-MAPK. His research spans multiple cancer types including ovarian, breast, and esophageal cancers, with particular emphasis on understanding the molecular basis of therapy resistance.

Boersma has published 23 research outputs with notable citations, including a 2015 Molecular Cancer paper that has received 75 Scopus citations. His work demonstrates strong collaborative patterns, frequently partnering with researchers such as Wiemer E., Mathijssen R., and Jaarsveld M. across multiple publications.

His research has significant implications for developing biomarkers to predict treatment response and for creating novel therapeutic strategies to overcome drug resistance in cancer patients.