معرفی
Todd Evans is a Professor at Weill Cornell Medicine, affiliated with the Department of Surgery and the Graduate School of Medical Sciences. He leads the Evans Laboratory, which is dedicated to understanding the molecular basis of organogenesis and its implications for human disease and regenerative medicine. His research spans developmental biology, stem cell biology, and epigenomics, with a strong focus on GATA transcription factors and signaling pathways in cardiovascular, hematopoietic, and gastrointestinal systems.
Dr. Evans earned his BA from Northwestern University and his PhD from Columbia University. He conducted postdoctoral research at the NIH, where he discovered the critical role of Gata1 in red blood cell development. He served on the faculty at the University of Pittsburgh and the Albert Einstein College of Medicine, where he became a tenured Professor and Dean of the Graduate Program, before joining Weill Cornell Medicine in 2009 to establish the Program in Stem Cell Biology and Regenerative Medicine in Surgery.
His research employs zebrafish, mouse, and human pluripotent stem cell models, including organoids, to study lineage commitment, differentiation, and morphogenesis. Key areas include the function of GATA4/5/6 in cardiogenesis, epigenomic regulation by TET enzymes and QSER1, and modeling diseases such as DiGeorge syndrome and chemotherapy-induced cardiotoxicity. His lab emphasizes independent student projects within a collaborative, cross-disciplinary environment.
Recent publications reflect a strong trend in using genetic and epigenetic tools to dissect developmental pathways and their dysregulation in congenital and acquired diseases, with applications in cancer, diabetes, and regenerative therapies. His work bridges basic science and translational medicine, aiming to identify novel therapeutic targets.
- Outstanding Investigator Award, NHLBI
- Pressman Professorship (endowed chair)
- NIH MERIT Award
- Samuel M. Rosen Outstanding Teaching Award
- Irma T. Hirschl, Career Scientist Award
- Established Investigator Award, American Heart Association
- Searle Scholar Award, Chicago Community Trust
- Basil O'Connor Scholar Award, March of Dimes Foundation
Dr. Evans has mentored numerous students and fellows, fostering a research environment that values discovery, collaboration, and mentorship. His lab has received significant grant support, enabling long-term investigations into developmental mechanisms. He has played a leadership role in shaping graduate education and research programs, both at Einstein and Weill Cornell.
The Evans Laboratory operates at the intersection of developmental biology and regenerative medicine, utilizing advanced animal and stem cell models to dissect the genetic and epigenetic networks that govern organ formation. The team is highly collaborative, with a culture that emphasizes rigorous science, supportive mentorship, and innovative approaches to understanding and treating human disease.
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