معرفی
Ting-Yu Lin is an Assistant Professor in Structural Biology at Durham University. Her research investigates RNA modification enzymes using biochemical and cryo-EM approaches, focusing on pseudouridine synthases linked to neurological disorders.
Research includes:
- Structural analysis of tRNA-modifying enzymes
- Mechanistic studies of pseudouridylation
- Pathogenic mutation characterization
- Cryo-EM of macromolecular complexes
- Enzyme-substrate specificity
Her work connects enzyme dysfunction to intellectual disability pathologies through biochemical and cell-based assays.
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