Tin A Than

Dr. Tin A Than serves as an Assistant Professor of Research Medicine at the University of Southern California, focusing on mitochondrial mechanisms in liver pathophysiology. His work bridges molecular biology and clinical hepatology through investigations of stress response pathways and developmental processes.

His educational background includes a medical degree from University of Yangon, Institute of Medicine and a PhD in Free Radical Biology & Molecular Biology from Okayama University Graduate School of Medicine and Dentistry. This dual training underpins his integrative research approach.

Dr. Than's primary research explores mitochondrial biogenesis, stress response, and mitophagy in liver disease contexts, with specific emphasis on reactive oxygen species regulation of gene expression. His current work centers on mitochondrial retrograde signaling and SAB protein interactions in metabolic liver disorders. Recent publications demonstrate consistent focus on JNK pathway dynamics and mitochondrial dysfunction across acute and chronic liver injury models.

His scientific contributions reveal strong thematic continuity in mitochondrial signaling research, with over 20 publications spanning from 2000-2024. Key trends include sex-dependent liver injury mechanisms, gut-liver axis interactions in microbiome studies, and therapeutic targeting of kinase pathways in drug-induced hepatotoxicity.

No scientific awards or major grants are documented in available sources. While student mentorship details are unavailable, his research program appears integrated within USC's translational medicine infrastructure through the CTSI profile.