Timothy C. Mueser

Timothy C. Mueser is a Professor in the Department of Chemistry & Biochemistry at the University of Toledo, affiliated with the College of Natural Sciences and Mathematics. His career spans roles at the University of Iowa, NIH, and Oak Ridge National Labs, focusing on structural biology and enzymology.

• Education: B.S. and Ph.D. in Chemistry, University of Nebraska-Lincoln
• Positions: NIH Postdoctoral Fellow, NIH Senior Staff Fellow, University of Toledo faculty since 2000

Research Interests include biophysical chemistry, macromolecular crystallography, and neutron diffraction studies of PLP-dependent enzymes (e.g., aspartate aminotransferase, tryptophan synthase). He investigates protein-DNA interactions in bacteriophage T4 and employs microgravity to enhance neutron diffraction crystal growth. His work bridges structural biology, enzymology, and biophysics.

Scientific Awards

• NSF CAREER award for gp59 helicase-loader research

Advising and Grants involve mentoring Ph.D. student Steven Dajnowicz and collaborations with Oak Ridge National Labs (Dr. Paul Langan, Dr. Leighton Coates) and NASA/CASIS for microgravity research. He has contributed to structural studies of hemoglobin, DNA replication, and enzyme mechanisms.