معرفی
Dr. Thomas Pulinilkunnil is a Professor in the Department of Biochemistry and Molecular Biology at Dalhousie University, affiliated with Dalhousie Medicine New Brunswick. He joined the faculty in 2012. His research focuses on nutrient regulation of lysosomal metabolism, autophagy, and BCAA biology in cardiometabolic and cancer contexts.
Education: PhD (University of British Columbia, 2005), Postdoctoral Fellowships at Harvard Medical School (2005-2008) and University of Alberta (2008-2012).
Research Interests: Metabolic regulation of autophagy, lysosomal function in disease, BCAA metabolism in health and disease, ER glycosylation disorders, and cancer metabolism. His lab uses rodent, zebrafish, and yeast models to study these pathways.
Publications: Over 60 peer-reviewed articles, with recent work on BCAA dysregulation in cardiometabolic disorders, TFEB's role in cancer cell survival, and lysosomal dysfunction in obesity-related heart failure. Key themes include nutrient-sensing pathways, mitochondrial-lysosome crosstalk, and translational applications in cancer therapy.
Awards/Grants: Not explicitly listed, but his research is supported by grants from institutions like Dalhousie Medicine New Brunswick and collaborations with Saint John Regional Hospital.
Labs/Teams: Leads the Pulinilkunnil Lab at Dalhousie, collaborating with teams like IMPART and CVRG. Current lab members include graduate students (e.g., Gurpreet Kaur, Max Merilovich) and postdocs (e.g., Sundaram Pakkirisami).
