معرفی
Hui Zheng, Ph.D. is a Professor and Director at Huffington Center on Aging, Baylor College of Medicine, Houston, Texas. She holds dual appointments in the Department of Molecular and Human Genetics and Department of Neuroscience. Her research focuses on Alzheimer’s disease (AD) pathogenesis through lysosomal dysfunction and neuroinflammatory mechanisms.
- Education: BS (Peking University, 1984), Ph.D. (Baylor College of Medicine, 1990), Postdoctoral Fellowship (Baylor, 1991-1993)
Research Interests include:
- Autophagy-lysosomal pathway in neurodegeneration
- Neuron-immune cell interactions in AD
- Complement signaling (C3/C3aR) in neuroinflammation
- Epoxy lipid metabolism as AD therapy
- TFEB signaling in protein clearance
Recent Publication Trends show expertise in lysosomal signaling, neuroinflammatory pathways, and lipid metabolism in AD models. Key subfields include tauopathy mechanisms, microglial homeostasis, synaptic dysfunction, and translational pharmacology.
Scientific Awards:
- Zenith Award, Alzheimer’s Association (2004-2006)
- New Scholars Award, Ellison Medical Foundation (2000-2004)
- NIH/NIA Neuroscience of Aging Review Committee Leadership (2003-2008)
Current Projects under NIH grants investigate:
- TFEB’s role in tau clearance
- Lysosome-to-nucleus signaling in aging
- Complement immunometabolism in AD
- Epoxy hydrolase inhibition for neuroprotection
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