Thomas Ouldridge

Thomas Ouldridge is a Royal Society University Research Fellow and Reader in Biomolecular Systems at the Department of Bioengineering, Faculty of Engineering, Imperial College London. He leads the 'Principles of Biomolecular Systems' group, which focuses on theoretical and computational modeling of complex biochemical systems, particularly exploring the interplay between molecular details and emergent behaviors like sensing, replication, and self-assembly. His work integrates natural systems analysis with synthetic biology applications, aiming to engineer artificial analogs of biological processes.

His research spans interdisciplinary areas including stochastic thermodynamics, DNA-based computation, and molecular reaction networks. Key affiliations include the Physics of Life, Synthetic Biology Hub, and the Leverhulme Centre for Cellular Bionics. He has contributed to over 60 peer-reviewed articles since 2009, with recent work emphasizing energy-efficient molecular information processing and thermodynamic limits of biochemical systems.

• Awards: Royal Society University Research Fellowship (current).
• Labs/Teams: Principles of Biomolecular Systems Group, collaborating with multiple centers including the Centre for Synthetic Biology and Institute of Chemical Biology.
• Grants/Positions: Maintains research funding through the Royal Society and UKRI grants, focusing on non-equilibrium biomolecular systems and synthetic biology tools.

Recent publications highlight advances in DNA templating networks, stochastic thermodynamic modeling of computation, and optimal protocols for molecular copying systems. His work bridges foundational physics with applied biotechnology, aiming to push the boundaries of synthetic biological engineering.