معرفی
Thomas C. Dowling is the Assistant Dean (Research) and Professor at Ferris State University's College of Pharmacy, where he also serves as Director of the Office of Research and Sponsored Programs. He holds a PharmD from Ferris State (1993) and a PhD in Pharmaceutical Sciences from the University of Pittsburgh (1999). His research focuses on pharmacokinetics, particularly drug absorption/distribution (ADME), and advancing kidney function assessment through metabolomics. He has secured over $4M in grants for projects involving experimental kidney models, FDA-regulated clinical trials, and collaborations with institutions like Baylor College of Medicine and Michigan State University. Notable contributions include developing LC-MS/MS assays for DFMO and co-authoring chapters in DiPiro’s Pharmacotherapy and Clinical Pharmacokinetics. Awards include AACP Teacher of the Year (2004). He actively advises students in the Shimadzu Core Lab and engages in professional service via FDA committees and ACPE accreditation roles. Current research explores DFMO dosing optimization and biomarkers for cirrhosis-related kidney dysfunction.
Education:
- PhD, University of Pittsburgh (1999)
- PharmD, Ferris State University (1993)
Research Interests:
- Pharmacokinetics of drugs in hepatic/kidney disease
- ADME modeling and clinical translation
- Metabolomics for kidney dysfunction prediction
- Experimental kidney models for drug testing
Publications Trends: Recent work emphasizes renal drug dosing, metabolomic biomarkers, and DFMO pharmacology. Over 30 peer-reviewed articles and book chapters since 2004 reflect his interdisciplinary approach to clinical pharmacology and translational research.
Awards:
- AACP Teacher of the Year (2004)
Grants & Advising: Secured $4M+ in funding; mentors students in analytical chemistry and pharmacokinetic studies. Collaborations include Baylor Medicine, University of Maryland, and Corewell Health.
Labs/Teams: Leads the Shimadzu Core Lab at Ferris State, focusing on LC-MS/MS applications in drug analysis.
