Thomas Bowden

Thomas Bowden serves as Professor of Structural Biology at the University of Oxford, affiliated with the Nuffield Department of Medicine and the Wellcome Centre for Human Genetics. His research centers on viral surface glycoproteins as targets for therapeutic intervention.

His laboratory integrates structural biology, immunology, and cell biology to decode glycoprotein structure-function relationships in enveloped viruses. Key research emphases include characterizing neutralizing monoclonal antibodies and identifying molecular vulnerabilities for rational vaccine design. The group's work directly informs therapeutic development against viral pathogens through biophysical insights into antibody-glycoprotein interactions.

Bowden leads a research team at the Wellcome Centre for Human Genetics, where they investigate paramyxoviral attachment glycoproteins and related viral structures to advance preventive and therapeutic strategies against infectious diseases.