معرفی
Taro Ueda is a Professor at the Faculty of Science and Engineering, School of Advanced Science and Engineering, specializing in Biophysics and Cell Biology. With a D.Sc. from the University of Tokyo, his research focuses on actin filament regulation, molecular motor proteins, and cytoskeletal mechanics across eukaryotic systems.
- Major research themes include: actin-myosin interactions, cofilin dynamics, and plant-specific cytoskeletal mechanisms
- Key techniques employed: high-speed atomic force microscopy, fluorescence microscopy, and X-ray crystallography
Research Trends from his 145+ publications (5645 citations, h-index 37) reveal consistent exploration of:
- Cooperative conformational changes in actin filaments
- Cytoskeletal specialization in plant cells (ACT2/ACT7 isoforms)
- Mechanical regulation of protein binding in contractile ring formation
- Evolution of motility systems across the Tree of Life
His work has advanced understanding of
- Directional allostery in actin regulation
- Plant-specific actin nucleators like CHUP1
- Nonmuscle myosin isoform differentiation
- Mechanisms of congenital myopathy mutations
Ueda's laboratory maintains active collaborations across institutions, with notable contributions to:
- Development of novel actin visualization techniques (Actin Painting)
- Elucidating structural equilibria in G protein-coupled receptors
- Nanoparticle-based cancer cell destruction methods
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Taro Ueda در جاهای دیگر
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