معرفی
Tamara Isakova, MD, MMSc, is the Fowler McCormick Professor of Nephrology and Professor of Medicine (Nephrology and Hypertension) at Northwestern University Feinberg School of Medicine. She concurrently serves as Chief of Nephrology and Hypertension in the Department of Medicine and as Director of the Institute for Public Health and Medicine (IPHAM) Center for Translational Metabolism and Health. Dr. Isakova is affiliated with the Feinberg Cardiovascular and Renal Research Institute and the Northwestern University Clinical and Translational Sciences Institute (NUCATS).
Education & Training
- MD: SUNY-Downstate Medical Center (2003)
- MMSc: Harvard Medical School (2009)
- Intern: Massachusetts General Hospital, Medicine (2004)
- Resident: Massachusetts General Hospital, Medicine (2006)
- Fellow: Massachusetts General Hospital & Brigham and Women’s Hospital, Nephrology (2010)
- Board Certified: Nephrology, American Board of Internal Medicine
Research Focus
Dr. Isakova’s translational program centers on disordered mineral metabolism in chronic kidney disease (CKD), integrating large-scale epidemiologic cohorts, randomized clinical trials, biomarker discovery, and patient-centered outcomes. Her work elucidates pathways linking FGF23, phosphate, vitamin D metabolites, and novel gut-derived factors to cardiovascular and renal endpoints. She leads the NIH-funded TRIDENT study, a multi-center cohort designed to redefine diabetic nephropathy through molecular phenotyping of kidney biopsies, and she heads the Chronic Kidney Disease Research Biorepository that supports biomarker validation across the translational continuum.
Clinical Trials & Grants
- Principal Investigator, Transformative Research in Diabetic Nephropathy (TRIDENT) – NIH multi-site prospective cohort (NCT02986984)
- Principal Investigator, Chronic Kidney Disease Research Biorepository – repository and outcomes study (IRB STU00201546)
- Co-Investigator, O’Brien Kidney Center grant – Northwestern received $5.8 million NIH award to expand kidney disease prevention research
Scientific Honors & Awards
- Elected Member, American Society for Clinical Investigation (2025)
- Elected Member, Association of American Physicians (2025)
- Department of Medicine Mentor of the Year (2021)
- Distinguished Mentor Award, American Society of Nephrology (2019)
- Feinberg School of Medicine Mentor of the Year (2019)
- Jack W. Coburn Endowed Lectureship, ASN Kidney Week (2017)
Leadership & Service
Dr. Isakova chairs or sits on multiple NIH and international data-safety monitoring boards, serves on the KDIGO Controversies Conference steering committee, and is Co-Chair of the ASN Kidney Week 2024 Program Committee. She is a Section Editor for Current Opinion in Nephrology and Hypertension and has held editorial roles with American Journal of Kidney Diseases and CJASN.
