Sumati V. Gupta

Sumati V. Gupta, MD, is a tenured Associate Professor in the Division of Oncology, Department of Medicine at the University of Utah's Huntsman Cancer Institute (HCI). She specializes in genitourinary cancers (bladder, kidney, prostate, testicular) and geriatric oncology. Dr. Gupta serves as Medical Director of the Geriatric Oncology Clinic (GOAL) and co-Principal Investigator of the Total Cancer Care project at HCI. She also practices at the Salt Lake City Veteran Administration hospital, where she chairs the VISN-19 Interdisciplinary Cancer Committee.

Education:

• MD: King Edward Memorial Hospital and Seth G.S. Medical College, Mumbai, India
• Residency: Internal Medicine, Nassau University Medical Center (SUNY Stony Brook)
• Fellowships: Geriatrics (Baylor College of Medicine), Medical Oncology (University of Utah)

Research Focus: Her work investigates treatment resistance mechanisms in genitourinary cancers, clinical trial design for targeted therapies (e.g., FGFR/PARP inhibitors), and biomarker discovery. She leads studies on immunotherapy combinations, radiotherapeutic approaches, and real-world treatment patterns in urothelial/prostate cancers.

Publications (Trends): Recent articles (2023-2025) emphasize phase II trials of novel agents (e.g., nivolumab, enfortumab vedotin), biomarker-driven therapies in FGFR-altered cancers, and real-world analyses of treatment attrition/disparities. Key themes include immunotherapy combinations, geriatric oncology considerations, and liquid biopsy applications.

Leadership & Grants: Co-chairs the Genitourinary Cancers Research Interest Group (ORIEN consortium) and serves on HCI's Data Safety and Monitoring Committee. Active in multi-center trials (e.g., TROPHY-U-01, NEXT, RadSABR) funded by industry/academic partnerships.

Clinical Teams: Leads the GOAL Clinic for older adults with cancer and collaborates with HCI's Experimental Therapeutics program. At VA hospitals, mentors residents/fellows and oversees genitourinary cancer research initiatives.