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Stéphane Descorps-Declère is a researcher and bioinformatician at the Institut Pasteur in Paris, France, where he currently serves as part of the Bioinformatics and Biostatistics HUB Team. With over 15 years of professional experience in bioinformatics and genomics, he has developed significant expertise at the intersection of computer science and biological research, focusing on practical applications for understanding pathogens and microbial systems.
His educational background includes:
- Ph.D. in Computer Science Applied to Biology (2002-2006) from Paris VI, INRIA, Grenoble
- DESS in Applied Computer Science to Biology (1999-2000) from UPMC
- Master's in Cell Biology and Animal Physiology (1997-1998) from UPMC
Dr. Descorps-Declère's research spans bioinformatics, genomics, and data analysis, with particular expertise in comparative metagenomics, genome analysis, and sequence analysis. His work bridges computational methodology and biological analysis, developing practical tools that advance our understanding of pathogens and genomic systems. He has published extensively on viral genome assembly, bacterial pathogenesis, and the analysis of genetic elements like microsatellites and megasatellites.
His publication record from 2015-2024 reveals a consistent research trajectory focused on genomic analysis techniques and their applications to infectious diseases. His work demonstrates expertise in viral genome reconstruction, bacterial virulence mechanisms, and genome architecture of pathogens, with significant contributions to methods for overcoming challenges in genomic data analysis.
Dr. Descorps-Declère has been actively involved in teaching for approximately the past ten years through the Pasteur's Central Teaching Committee. He has taught multiple courses including 'From genes to function: a survival guide to web-based tools for microbiologists' (2019) and several iterations of 'Introduction to data analysis' (2017, 2018), training graduate students and researchers in essential bioinformatics skills.
He is currently involved in research projects including 'CNF1 and Rho GTPases ubiquitylation in cellular invasion by uropathogenic E. coli,' working as part of a team led by Emmanuel Lemichez. His bioinformatics expertise supports investigations into how bacterial toxins manipulate host cellular processes during infection.
