Stine Lind Hansen

Stine Lind Hansen is a Postdoctoral Researcher at the Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, where she works in the Jensen Lab at reNEW (The Novo Nordisk Foundation Center for Stem Cell Medicine). Her research focuses on intestinal stem cell biology, epithelial cell fate decisions, and inflammatory bowel disease mechanisms, particularly using organoid technology to model intestinal development and disease processes in ulcerative colitis.

Dr. Hansen's primary research interests include:

• Intestinal stem cell differentiation and maintenance
• Signaling pathways in intestinal development (particularly YAP/TAZ and JAK/STAT)
• Cell fate decisions in colonic epithelium
• Organoid-based modeling of intestinal diseases
• Host-microbe interactions in the gut
• Molecular mechanisms of inflammatory bowel disease

Her publication record shows a consistent focus on understanding the molecular regulators of intestinal epithelial maturation and how these processes are disrupted in disease states. She has employed cutting-edge techniques including CRISPR-Cas9 screening, transcriptional and epigenomic profiling, and fate mapping in mouse models to investigate fundamental questions in intestinal biology.

Dr. Hansen has published in high-impact journals including Cell Stem Cell (with a highly cited 2018 paper showing over 480 citations), Science Advances, Developmental Cell, and Stem Cell Reports. Her work has contributed significantly to understanding how signaling pathways like YAP/TAZ regulate tissue regeneration and how vitamin D receptor signaling influences cell fate decisions in ulcerative colitis.

She maintains an active research profile with publications extending to 2025, demonstrating ongoing contributions to the field of intestinal stem cell biology and inflammatory bowel disease research.