Martti Maimets

Martti Maimets serves as an Associate Professor in the Department of Biomedical Sciences at the University of Copenhagen's Faculty of Health and Medical Sciences. He is affiliated with reNEW (a stem cell research center) and the Jensen Lab, focusing on intestinal biology and stem cell research. His work bridges basic science with clinical applications in gastrointestinal diseases.

His research interests center on intestinal stem cell biology, organoid technology, and signaling pathways including Wnt, Shh, and JAK/STAT. These areas are critical for understanding intestinal development, homeostasis, and disease mechanisms, particularly in inflammatory bowel diseases like ulcerative colitis. His laboratory employs advanced techniques including fate mapping, transcriptional profiling, and proteomics to investigate cellular differentiation and tissue regeneration.

Maimets' recent publications demonstrate a strong focus on how signaling pathways regulate intestinal epithelium maturation and regionalization. His work with organoid models has provided insights into host-microbe interactions and disease mechanisms. The research shows a clear trajectory toward understanding the molecular basis of gastrointestinal diseases and developing potential therapeutic approaches.

His scientific contributions include significant publications in high-impact journals such as Nature Communications, Cell Stem Cell, and Science Advances. His work on mesenchymal-epithelial crosstalk and YAP signaling has been particularly influential in the field of intestinal development.

Maimets actively collaborates with researchers across multiple institutions, as evidenced by his co-authorship on numerous publications. His work with primary epithelial organoids represents an important methodological contribution to the field, allowing for more accurate modeling of human intestinal biology.