معرفی
Steven Gross is a Professor in the Department of Pharmacology at the Weill Cornell Graduate School of Medical Sciences, with a research focus on nitric oxide (NO) signaling in mammalian cells. His work spans molecular pharmacology and cell signaling, particularly in cardiovascular and cancer contexts.
- Key contributions include identifying L-arginine as NO's precursor and demonstrating NO's role in vascular tone regulation.
- His lab explores NO synthase (NOS) mechanisms, therapeutic targeting of NO pathways, and metabolic liabilities in diseases like septic shock and diabetes.
Research Themes include:
- Elucidating how NO regulates vascular tone, neuronal signaling, and host defense.
- Investigating NO overproduction in septic shock and its therapeutic downregulation.
- Linking NO to mitochondrial metabolism and cancer cell proliferation.
- Developing NO-based drugs through biotech startup ArgiNOx Inc.
Scientific Awards:
- Founder and Board Director of the Nitric Oxide Society, organizing annual international meetings and publishing peer-reviewed journals.
Advising includes mentoring graduate students in pharmacology, such as Tal Nuriel, Alex Hansler, and Pamela Wille. His lab collaborates with institutions like Sloan Kettering Institute and Mount Sinai School of Medicine.
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