معرفی
Steven Gross, PhD is a Professor of Pharmacology at Weill Cornell Medical College. His research focuses on chemical mechanisms of cell signaling by reactive molecules (notably nitric oxide) and metabolite profiling technologies for disease characterization. His work bridges Bioorganic Chemistry and Systems Pharmacology through chemical probe development and mass spectrometry imaging.
- Education: PhD (1984) from Mount Sinai School of Medicine, BS (1973) from Brooklyn College
Key research areas include:
- Redox signaling via nitric oxide and peroxynitrite
- Untargeted metabolomics for disease states and drug effects
- Chemical methodology for post-translational modifications
- Macromolecular structure-function relationships
Recent publications (2025-2023) demonstrate expertise in
- Metabolic reprogramming in cardiac and liver diseases
- Epigenetic regulation in developmental defects
- Novel imaging metabolomics techniques
- Pigmentation and melanosomal pH dynamics
- Biomolecular condensate formation
Current funding includes grants from NIH institutes (NIDDK, NINDS) and American Heart Association for studies on
- NAD+ metabolism in obesity-related diseases
- Metabolic landscape of brain ischemia
- AMPK and mitochondrial myopathies
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