Stephen Nishimura

Stephen Nishimura is a Professor in the University of California, San Francisco School of Medicine's Department of Pathology. His research focuses on integrin-mediated activation of transforming growth factor beta (TGF-β) and its role in various diseases. He maintains an active clinical profile at UCSF Medical Center and has been continuously funded by NIH grants since 1995.

Research Interests center on

• Integrin biology and TGF-β signaling
• Pulmonary disease mechanisms (particularly COPD)
• Vascular pathology and endothelial cell function
• Immunoregulation in tumor microenvironments
• Epithelial-mesenchymal interactions

Publication Trends show consistent contributions to Cell Biology, Immunology, and Pulmonary Medicine, with recent emphasis on structural analysis of TGF-β activation and integrin sulfhydration mechanisms. His work demonstrates integrin αvβ8's critical role in immune regulation and tissue homeostasis across multiple disease models.