Smaragda Kompocholi

Smaragda Kompocholi is a Research Fellow in the Department of Cellular and Molecular Medicine at the University of Copenhagen, actively contributing to the Gregersen group's research on RNA processing-transcription interplay through RNA polymerase II associated factors.

Her work centers on molecular mechanisms of genome stability, with specialized expertise in DNA repair pathways involving helicases like ZGRF1. Research spans transcription-coupled repair, recombinational DNA damage resolution, and fertility maintenance using murine and human cellular models, reflecting interdisciplinary integration of molecular biology, genetics, and reproductive science.

Recent publications demonstrate consistent focus on ZGRF1's role across biological systems, with the 2025 Heliyon study extending 2020 Cell Reports findings from human cells to mouse fertility models. This trajectory highlights translational research bridging DNA damage response mechanisms with reproductive health outcomes.

The Gregersen group operates within Copenhagen's Transcription, RNA, and Gene Medicine Program, maintaining collaborative networks evident in multi-institutional publications with researchers from Denmark, Spain, and the UK.