Ernest Wee Kiat Lim

Ernest Wee Kiat Lim is a Research Fellow in the Department of Biology at the University of Copenhagen's Faculty of Science, affiliated with the Functional Genomics research group. His work focuses on molecular mechanisms in DNA repair, cancer biology, and antimicrobial research using mouse models and peptide nucleic acid technologies.

He completed his PhD in 2024 at the University of Copenhagen with a thesis titled "Characterising the Organismal Role of ZGRF1 in Mus Musculus", investigating ZGRF1 helicase in DNA repair and fertility.

Lim's research spans molecular biology and genetics, emphasizing DNA repair pathways, B-cell lymphoma development, and novel antimicrobial/gene therapy strategies using peptide nucleic acids (PNAs). His work integrates functional genomics and in vivo models to address genomic instability and therapeutic delivery challenges.

His 2020-2025 publications show an evolution from PNA delivery systems for muscular dystrophy toward DNA repair mechanisms in fertility and cancer. Key themes include PNA applications for splice-switching and antimicrobial activity, and helicase roles (ZGRF1/PICH) in genomic integrity maintenance.

No scientific awards were mentioned in available records.

Supported by a PhD fellowship during doctoral studies, Lim continues research funding through the Functional Genomics group. As an early-career researcher, he has not supervised students but collaborates extensively on grant-funded projects.

He operates within the Functional Genomics laboratory led by Professors Michael Lisby and Ian Hickson, utilizing mouse genetics, molecular cloning, and fluorescence imaging to study DNA repair and nucleic acid therapeutics.