Nicolas Nieto Moreno

Nicolas Nieto Moreno is a Researcher at the Department of Cellular and Molecular Medicine within the Faculty of Health and Medical Sciences at the University of Copenhagen. He is affiliated with the Transcription, RNA, and Gene Medicine Program in the Svejstrup research group, focusing on molecular mechanisms of DNA repair and transcription regulation.

His research centers on transcription-coupled DNA repair processes, particularly how cells resolve RNA polymerase II stalling at DNA lesions caused by ultraviolet radiation. He investigates kinase-mediated clearance mechanisms (notably STK19) and the cellular response to genotoxic stress, contributing to fundamental understanding of genome maintenance pathways.

Recent publications in Cell (2024) and the Annual Review of Biochemistry (2023) demonstrate his expertise in nucleotide excision repair and transcriptional responses to DNA damage. These works reveal critical protein interactions in lesion clearance and establish frameworks for understanding transcription-repair coupling, with significant implications for cancer research and genetic disorders.