Sigrid Milles

Sigrid Milles is a Junior Group Leader and Head of the Milles Group at the Leibniz Research Institute for Molecular Pharmacology (FMP) in Berlin. Her research focuses on structural biology, particularly the study of intrinsically disordered proteins (IDPs) in clathrin-mediated endocytosis.

Her work integrates single-molecule fluorescence spectroscopy and NMR spectroscopy to analyze the molecular mechanisms of IDPs and their linear motifs in cellular processes. Recent publications highlight her innovative approaches to combining these techniques for studying dynamic protein systems.

Key research areas:

• Clathrin-mediated endocytosis
• IDP dynamics and structural propensities
• Integrative structural modeling

Students:

• Andromachi Papagiannoula (PhD Student)