معرفی
Dr. Shu-Yu Chen is a Researcher at ETH Zurich, affiliated with the Institute of Molecular Physical Sciences (IMPS). Their work focuses on molecular mechanisms of protein interactions, enzymology, and drug discovery. Key research areas include protein-protein interaction stabilization, γ-secretase modulation, and antibiotic development targeting bacterial pathways. They utilize advanced techniques like molecular dynamics simulations and chemical proteomics. Dr. Chen's recent publications explore ternary complex formation, membrane protein interactions, and novel antibiotic mechanisms.
Research interests are centered on understanding biochemical processes at the molecular level, with applications in therapeutic design. Their contributions span computational biophysics, enzyme-substrate dynamics, and structural biology. Dr. Chen collaborates on projects involving molecular glue design, lipoate salvage pathway inhibitors, and Alzheimer's-related γ-secretase mechanisms.
Publications highlight interdisciplinary approaches to studying membrane proteins, protein interactions, and enzymatic processes. Current work emphasizes developing tools to characterize complex biochemical systems and translating findings into novel therapeutic strategies.
