Shiyong Wu

Shiyong Wu is a Professor in the Department of Chemistry and Biochemistry within the College of Arts and Sciences at Ohio University. His research focuses on molecular mechanisms of UV radiation-induced skin cancer, DNA damage, cell stress responses, and cancer signaling pathways. He is based at the Konneker Research Center on the Athens Campus.

Research Interests: Dr. Wu's work centers on molecular carcinogenesis, particularly the roles of proteins like CIRP, prohibitin, and NF-κB in skin cancer development. His lab explores oxidative stress, chemoprevention using natural compounds like carnosol, and the regulation of apoptosis and cell survival after UVB exposure. He also investigates cancer metastasis, integrin signaling, and the impact of obesity and metabolic pathways on breast cancer progression.

The recent publications (2014–2018) reflect a strong focus on UVB-induced cellular responses, DNA repair mechanisms, and signaling cascades in skin and breast cancers. His work spans in vitro models, co-culture systems, and molecular techniques, with an emphasis on stress-induced gene regulation and chemopreventive strategies.

Scientific Awards:

Advising and Grants: Dr. Wu leads an active research lab involving graduate students and collaborators. While specific grant details are not listed, his extensive publication record suggests sustained funding in cancer biology and photobiology. He has mentored research that appears in high-impact journals such as Oncotarget, Scientific Reports, and Cancer Letters.

Labs and Teams: Dr. Wu runs a research laboratory at Ohio University, collaborating with scientists including Li Zuo, Liling Tang, Lingying Tong, and John J. Kopchick. His team employs techniques in molecular biology, cell culture, protein analysis, and mass spectrometry to study cancer mechanisms.