معرفی
Dr. Shin-Ichiro Hiraga is a Senior Lecturer at the University of Aberdeen's School of Medicine, Medical Sciences and Nutrition, based at the Institute of Medical Sciences. His research focuses on mechanisms of chromosome maintenance and DNA replication, using yeast and human cell models. He investigates RIF1 and SAF-A proteins' roles in replication stress response and epigenetic regulation. Key collaborators include Prof. Anne Donaldson and international researchers from institutions like Osaka University and the Crick Institute.
Education: BSc (1990) and PhD (1996) from Osaka University. He holds a Fellowship of the Higher Education Academy (FHEA, 2023). Professional memberships include the Biochemical Society, Genetics Society, and Molecular Biology Society of Japan. He serves as an editorial board member for Journal of Biochemistry and reviewer for high-impact journals.
Research interests span DNA replication initiation, fork protection, and epigenetic stability. His work bridges fundamental biology and translational applications in cancer prevention. Techniques used include proteomics, super-resolution microscopy, and genome-wide approaches. Major grants include a £1.5M Cancer Research UK Programme Award (2017) and a Daiwa Anglo-Japanese Foundation grant (2019).
Teaching responsibilities include advanced molecular biology and biochemistry courses. His lab explores how chromatin structure and protein complexes regulate DNA replication under stress conditions, with recent findings on SAF-A's role in 3D genome organization and replication robustness.
