Shehzad Sheikh

Shehzad Sheikh, MD, PhD is an Associate Professor in the Department of Medicine at the UNC School of Medicine, specializing in Inflammatory Bowel Disease (IBD) management. He bridges mucosal immunology, epithelial cell biology, and genomics through translational research.

• Physician-Scientist with clinical focus on IBD
• Director of IBD Tissue and Genomics Core
• Integrates multi-omics data with functional validation

His work includes high-throughput sequencing of RNA, chromatin, and small RNA from IBD tissues and immune cells, with recent emphasis on SUMOylation, microRNA biomarkers, and epigenetic regulation in mucosal inflammation. Awards:

• Pilot and Feasibility Award (2012, 2018)

Current research explores gene-environment interactions and personalized therapies through collaborations with Sartor, Sethupathy, and Furey labs. Contact: shehzad_sheikh@med.unc.edu