معرفی
Shaoning Jiang is an Assistant Professor in the Department of Pathology at Yale University School of Medicine. Her research focuses on epigenetic mechanisms linking inflammation and energy metabolism in diabetes and obesity. She holds affiliations with the Diabetes Research Center and investigates developmental origins of metabolic diseases, particularly the effects of maternal overnutrition on fetal programming.
Education:
- PhD in Molecular and Cellular Pathology, University of Alabama at Birmingham (UAB)
- Postdoctoral Training: UAB and University of Oklahoma Health Science Center (OUHSC)
- MD and MM from Peking University Health Science Center
Research Interests: Shaoning's work centers on two main areas:
- Macrophage-Mediated Regulation of Adipose Stem Cells: Examines miR-130b/301b's role in beige adipogenesis and energy metabolism, leveraging knockout mouse models and EV-based therapies.
- Developmental Programming of Metabolic Disorders: Investigates AMPK and mitochondrial pathways in placental development under maternal diabetes/obesity, with a focus on early prevention strategies.
Publications: Recent work highlights microRNA roles in metabolic diseases (e.g., miR-130b/301b's impact on beige fat), hepatocellular carcinoma metabolism, and fetal programming effects. Trends show integration of epigenetic mechanisms with clinical translation in metabolic disorders.
Grants & Advising: Details not explicitly listed, but her research implies NIH-funded projects. No students listed, though collaborations with Wenyi Luo and Yibo Xi suggest mentorship roles.
Labs/Teams: Leads projects at Yale Pathology and the Diabetes Research Center, focusing on translational epigenetic and metabolic research.
