معرفی
Dr. Shab Mohammadi is a Postdoctoral Researcher in the Molecular Evolutionary Biology research group at the University of Hamburg, Faculty of Mathematics, Informatics and Natural Sciences, Department of Biology, Institute for Cell and System Biology of Animals. She works under Prof. Dr. Susanne Dobler's research group focusing on molecular evolution, particularly of the ATP1A (Na+K+ATPase) gene family.
Her educational background includes:
- Postdoc at University of Nebraska-Lincoln (current)
- Ph.D. from Utah State University (2017)
- M.S. from Old Dominion University (2007)
- B.S. from George Mason University
Dr. Mohammadi's research focuses on the molecular evolution of ATP1A (Na+K+ATPase) gene family and the adaptability of vertebrates against cardiotonic steroids (bufadienolides and cardenolides). Her work involves functional analyses of Na+K+ATPases, with particular emphasis on how intramolecular epistasis has influenced the evolution of the enzyme's resistance to cardiotonic steroids. This research bridges evolutionary biology, molecular biology, and comparative physiology, examining how different species have evolved resistance to toxins through specific molecular changes in the Na+K+ATPase enzyme.
Her publication record shows a strong focus on molecular adaptation to toxins, particularly examining Na+K+ATPase variations across different species that have evolved resistance to cardiotonic steroids. Her work spans multiple disciplines including molecular biology, evolutionary genetics, comparative physiology, and herpetology, with a particular emphasis on snakes and amphibians that have co-evolved with toxic prey. Recent publications demonstrate increasingly sophisticated analyses of epistatic interactions and co-adapted amino acid substitutions that enable toxin resistance.
Dr. Mohammadi has also contributed to biology education research, developing active learning approaches for teaching evolution concepts in general biology curricula.
