معرفی
Dr. Sean Munro is a Research Fellow at the MRC Laboratory of Molecular Biology, University of Cambridge. His research focuses on understanding the molecular mechanisms governing membrane trafficking and organelle identity, particularly within the Golgi apparatus. Utilizing biochemical, genetic, and structural approaches, he investigates how G proteins and phosphoinositides define organelle specificity and mediate vesicle tethering.
Research priorities include:
- Organelle identity determination via Arf/Rab G proteins
- Phosphoinositide lipid signaling in trafficking
- Structural characterization of Golgi tethering proteins
- Comparative analysis using Drosophila models
Recent publications highlight his work on TBC1D23-mediated vesicle bridging, Golgi structural organization, and COPI adaptor functions. Current projects examine carrier recognition mechanisms and golgin protein dynamics.
Key collaborators include Alison Gillingham, Jessica Chadwick, and researchers from the Cambridge Structural Biology community.
