معرفی
Dr. Sean Meaden is a BBSRC Discovery Fellow at the University of York's Department of Biology. His research focuses on bacterial-phage interactions, CRISPR-Cas systems, and microbial ecology, with a particular emphasis on evolutionary and ecological processes shaping these dynamics. He holds a Marie-Skłodowska Curie Fellowship and has conducted postdoctoral work at UC Berkeley and the University of Otago. His current work uses Hi-C sequencing and Nanopore techniques to study phage infections in soil microbial communities. He also contributes to outreach through programs like Phages for Global Health, promoting phage biology education in developing countries.
Education includes a PhD from the University of Exeter (supervised by Prof. Britt Koskella), examining bacterial resistance evolution in Pseudomonas syringae. His postdoctoral research with Prof. Edze Westra at Exeter and Prof. Peter Fineran at Otago advanced CRISPR-Cas studies in Pseudomonas aeruginosa and environmental metagenomics, respectively.
Research interests span CRISPR defense mechanisms, viral diversity impacts on microbial immunity, and the role of environmental conditions in resistance outcomes. His work bridges experimental evolution, genomics, and metagenomics to address fundamental questions in microbial ecology and evolution.
Key awards include the BBSRC Discovery Fellowship (2019-present) and the Marie-Skłodowska Curie Global Fellowship (2019). He has developed the PADLOC web server for identifying antiviral defense systems and collaborates internationally on projects like Phages for Global Health. His research highlights the importance of soil ecosystems as diverse microbial habitats critical to plant and environmental health.
