Sean Mcginty

Dr. Sean Mcginty is a Reader in Biomedical Engineering at the University of Glasgow's School of Engineering, where he leads research at the intersection of mathematical modeling, cardiovascular medicine, and drug delivery systems. He also serves as Senior Senate Assessor for Student Conduct within Academic Services. Previously, he directed the Centre for Mathematics applied to the Life Sciences (CMALS) from 2016-2024 and has held leadership roles in several professional organizations.

Mcginty's research focuses on developing mathematical and computational tools to understand biological processes, disease mechanisms, and treatment approaches. His work particularly emphasizes cardiovascular medical implant design, drug delivery systems, and mathematical modeling of percutaneous coronary intervention with stents and balloons. He is renowned for pioneering work in computational modeling of drug-eluting stents, including developing the first predictive model of in vivo drug-eluting stent performance and the first continuum computational model of restenosis subject to drug delivery from stents. His research group, MaCBE (Mathematical and Computational Biomedical Engineering), collaborates with experimental groups, clinical centers, and industry partners to advance healthcare through machine learning and AI applications.

Analysis of Dr. Mcginty's recent publications reveals a strong focus on computational modeling of drug delivery systems, particularly for cardiovascular applications. His work spans from fundamental mathematical approaches like constrained Bayesian optimization and Laplace transform modeling to practical applications in stent and balloon-based drug delivery. A consistent theme is the application of mathematical rigor to solve complex biomedical problems, with increasing emphasis on patient-specific modeling and multiscale approaches that bridge molecular mechanisms with clinical outcomes.

• Prof Tom Gibson Memorial Prize for pioneering work in mathematical modeling of PCI procedures and devices
• Fellow of The Institute of Mathematics & its Applications (FIMA)
• Chartered Mathematician (CMath)

Dr. Mcginty has extensive experience in knowledge exchange and impact culture, having served as Director of CMALS from 2016-2024 and as School lead for Impact Culture since 2022. He has collaborated with numerous companies and clinicians to ensure his research remains relevant and driven by clinical need. His work has resulted in significant grants, including a major EPSRC grant enabling the creation of The EPSRC Centre for Future PCI Planning. He actively engages with the public through events like the Glasgow Pint of Science festival and has organized the College-wide Images of Impact Competition.

As director of the European Special Interest Group on 'Implantable Devices and Drug Delivery Systems' under the European Consortium for Mathematics in Industry (ECMI), Dr. Mcginty leads an international team advancing research in cardiovascular medical devices. His laboratory combines mathematical modeling expertise with experimental validation through collaborations with clinical partners and industry, creating a robust ecosystem for translating theoretical advances into practical medical solutions.