Saami K. Yazdani

Saami K. Yazdani is a Professor at Wake Forest University, focusing on cardiovascular disease prevention and treatment through interdisciplinary methods combining engineering and biology. His research spans solid/fluid mechanics, tissue engineering, and physiological modeling to address vascular pathology and device failure.

Recent publications highlight advancements in drug delivery systems (e.g., stent-grafts, coated balloons), vascular closure devices, and mechanosensing in smooth muscle cells. His work emphasizes preclinical models, pharmacokinetic analysis, and translational applications for peripheral and coronary artery diseases.

Key contributions include ex vivo bioreactor systems, RNA ligands for reendothelialization, and comparative studies of drug-eluting versus bare-metal stents. Methodologies integrate computational modeling, experimental validation, and clinical correlation to improve device efficacy and vascular healing.