Scott J. Hasty

Scott J. Hasty is a Professor in the Department of Chemistry and Biochemistry at the University of Missouri, St. Louis. His research focuses on advanced carbohydrate chemistry and synthetic methodologies for oligosaccharide assembly.

His primary research interests span Carbohydrate Chemistry, Organic Synthesis, and Glycosylation Methods. Hasty specializes in developing novel glycosyl donors like the S-benzimidazolyl (SBiz) platform, enabling versatile strategies for oligosaccharide synthesis under diverse activation conditions. His work bridges fundamental organic chemistry with applications in glycobiology.

Recent publications demonstrate expertise in universal-activation glycosyl donors, showing high-yield glycosylations for both armed and disarmed substrates. Key trends include stable N-alkylated SBiz moieties compatible with strong basic conditions and Lewis acid-mediated coupling protocols.

Hasty collaborates extensively with Alexei V. Demchenko and receives funding from the National Institute of General Medical Sciences (Grant GM111835). His research contributes to chemical biology and pharmaceutical development through precise oligosaccharide construction.