معرفی
Saverio Tardito is an Honorary Associate Professor at the School of Cancer Sciences, University of Glasgow. His research focuses on cancer metabolism, particularly the role of amino acids and metabolic pathways in leukemia, glioblastoma, and other cancers. He has contributed to studies on drug repurposing, cell culture media optimization, and mitochondrial metabolism in therapy-resistant cancer cells. His work highlights vulnerabilities in cancer stem cells, such as arginine dependency and pyruvate anaplerosis. Tardito’s research also explores the applications of physiological cell culture media to improve model accuracy for cancer studies. He collaborates extensively on projects involving metabolic enzymes, such as glutamine synthetase and PYCR1, and their roles in tumor growth and survival.
His recent studies include identifying lomerizine as a mitochondrial metabolism inhibitor for chronic myeloid leukemia and developing the Plasmax medium to enhance placental stem cell function. Tardito’s publications span over 39 articles, covering topics from HIV-1 infection metabolism to microbiome-derived carnitine mimics. His research bridges basic metabolic mechanisms with translational applications in oncology and virology.
