Sascha Alexander Tuchman

Sascha Alexander Tuchman, MD, MHS is Professor of Medicine at the University of North Carolina (UNC) Chapel Hill School of Medicine where he serves as Associate Chief for Outpatient Clinics and Outreach, Director of the Multiple Myeloma and Amyloidosis Program, and Clinic Medical Director for Malignant Hematology. His clinical practice and research focus on plasma cell disorders, with special expertise in multiple myeloma, amyloidosis, and geriatric oncology.

Dr. Tuchman's research interests center on plasma cell disorders with particular emphasis on amyloidosis and the management of older, frail patients with multiple myeloma. His work addresses critical challenges in treating elderly patients with hematological malignancies, integrating geriatric assessment into oncology practice, and developing novel therapeutic approaches for plasma cell disorders. He has contributed significantly to advancing the understanding and treatment of monoclonal gammopathies and related conditions.

His recent publications demonstrate a consistent focus on multiple myeloma treatment strategies, particularly for refractory disease and special populations. His research spans clinical trials, consensus guidelines development, and translational studies addressing treatment resistance, novel therapeutic combinations, and personalized approaches for patients with plasma cell disorders. The work frequently addresses the unique challenges of managing myeloma in elderly patients and those with comorbid conditions.

• International Myeloma Working Group member
• International Society for Amyloidosis member
• Multiple myeloma committee in the Alliance cooperative cancer research group

As Director of the Multiple Myeloma and Amyloidosis Program at UNC, Dr. Tuchman mentors trainees interested in myeloma and related conditions. His leadership extends to designing research and formulating guidelines for managing plasma cell disorders through his participation in major international expert groups. His clinical program serves patients across North Carolina with specialized expertise in complex plasma cell disorders.