Sankari Nagarajan

Dr. Sankari Nagarajan is a Lecturer in Chromatin Biology at the Division of Molecular & Cellular Function, University of Manchester. She holds the CRUK Career Establishment Award and leads research on enhancer regulation and transcription factors in aggressive cancers. Her work focuses on drug resistance and metastasis in breast and prostate cancers using CRISPR-Cas9, single-cell epigenomics, and functional genomics.

Education:

• Doctor of Philosophy (2015): Role of BRD4 and histone acetylation in ER+ breast cancers, Georg-August-Universität Göttingen
• Integrated M.Sc. (2010): Bio-Medical Science, Bharathidasan University, India

Research Interests:

• Chromatin architecture proteins in endocrine resistance
• SWI/SNF complex role in ER+ breast cancers
• Single-cell epigenomics in metastasis
• Enhancer-derived RNAs as biomarkers

Awards:

• CRUK Career Establishment Award (2021-2027)
• UKIBCS Poster Prize (2020)
• EMBO Poster Prize (2018)

Grants & Projects:

• Principal Investigator in Manchester Breast Centre and Manchester Cancer Research Centre
• Leading projects on precision breast cancer prevention and tumor radioresistance