معرفی
Sandeep Kumar Mishra, PhD, is an Associate Research Scientist in the Department of Radiology & Biomedical Imaging at Yale School of Medicine, where he holds a primary appointment in the Magnetic Resonance Research Center within the Division of Bioimaging Sciences. He completed his doctoral training at Pondicherry University (2017) and finished post-doctoral research at Yale in 2024 before transitioning to his current research-intensive faculty role.
Education:
- PhD, Pondicherry University – 2017
- Post-doctoral Associate, Yale University – 2024
Research Focus: Mishra’s work integrates multinuclear magnetic resonance spectroscopy, responsive paramagnetic probes, and nano-constructs to quantify the tumor microenvironment. Major themes include in-vivo mapping of interstitial pH and sodium gradients in gliomas, development of Fe(II)/Co(II)/Ni(II)-DOTA tetraglycinate complexes for simultaneous pH–temperature sensing, and engineering dual-modal nano-agents that couple MR angiography with therapeutic delivery (chemo-photothermal, cryo-ablation, MMP inhibition).
Publication Trends: Across 28 peer-reviewed articles (2016-2025) he demonstrates a sustained trajectory in cancer imaging, moving from theranostic nanoparticles toward sophisticated spectroscopic imaging of tumor acid–base and ionic homeostasis, with increasing translational orientation involving rodent glioma and hepatocellular carcinoma models.
Collaborations & Affiliations: He is embedded in Yale’s inter-disciplinary MR research ecosystem, collaborating recurrently with faculty in Radiology, Biomedical Engineering, and the Magnetic Resonance Research Center (D. Coman, F. Hyder, P. Herman, J. Verhagen, J. Santana, A. Shewarega).
Contact: sandeepkmishra11@gmail.com | Magnetic Resonance Research Center, 300 Cedar Street, New Haven, CT 06519, USA
