معرفی
Sampada Chande is an Associate Research Scientist in the Department of Pathology at Yale School of Medicine, affiliated with the Nguyen Lab. She holds a PhD in Biotechnology from the National Environmental Engineering Research Institute (NEERI), Nagpur, India (2014) and completed postdoctoral training at Yale under Dr. Clemens Bergwitz. Her research focuses on cancer metastasis mechanisms, phosphate transporter biology, bone mineral metabolism, and skeletal muscle physiology.
Education
- PhD in Biotechnology, NEERI, Nagpur (2014)
- Postdoctoral Fellowship, Yale School of Medicine (2020)
Research Interests
Dr. Chande investigates molecular pathways governing lung cancer brain metastasis, particularly the role of RhoA signaling in osimertinib resistance. She also studies phosphate transporters (SLC20A1/PIT1) in skeletal muscle function and aging-related decline. Her work bridges oncology, cell biology, and biochemistry, with recent projects examining histological progression of NSCLC metastases and phosphorus bioavailability in mouse models.
Recent Article Trends
Her publications emphasize translational research across oncology (brain metastasis mechanisms), muscle physiology (aging-related functional decline), and nutritional science (phosphate bioavailability). Key themes include molecular characterization of metastatic progression, genetic engineering to model transporter deficiencies, and systems biology approaches to study metabolic regulation.
Labs & Collaborations
Primary affiliation: Nguyen Lab (focusing on metastasis research). Collaborations include work with Dr. Anna Arnal Estape (2 publications), Dr. Don Nguyen (2 publications), and Dr. Veronica Chiang (2 publications).
