Salvatore SUTTI

Salvatore SUTTI is an Associate Professor in the Department of Health Sciences at Università degli Studi del Piemonte Orientale "Amedeo Avogadro". His research focuses on the pathogenesis of nonalcoholic steatohepatitis (NASH), hepatocellular carcinoma (HCC), and related metabolic and inflammatory mechanisms. Key interests include the role of cytokines (e.g., Oncostatin M), immune signaling pathways (e.g., ICOS/ICOSL), and dietary interventions (e.g., ketogenic diets) in liver disease progression.

His work links oxidative stress, macrophage activation, and fibrosis to NASH-related carcinogenesis. He explores therapeutic strategies targeting immune-inflammatory pathways and molecular mediators like histidine-rich glycoprotein and osteopontin. Recent studies highlight the dual effects of dietary patterns on liver and skeletal muscle health in metabolic dysfunction.

Collaborations span immunology, hepatology, and nanotechnology. Projects include investigating co-stimulatory molecules in liver repair and fibrosis, funded through his role as Principal Investigator on the project Ruolo di molecole co-stimolatorie nella regolazione dei processi di guarigione del danno epatico e nello sviluppo di fibrosi.